A microscopic organism from a freshwater pond is playing by a different set of genetic rules. The newly identified protist, ...
When the coronavirus SARS-CoV-2 turned our world upside down, mRNA vaccines against COVID-19 brought a breakthrough. Their ...
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A pond microbe at Oxford breaks the genetic code, reading two stop signals as amino acids
A single-celled organism scooped from an artificial pond in Oxford University Parks reads the stop signals UAA and UAG as two ...
Scientists discover why ribosomes misread certain modified mRNA sequences and show how simple sequence changes could improve vaccine design and safety.
Terminal events in protein synthesis were studied with trinucleotide codons. Initiator and terminator trinucleotides sequentially stimulate N-formyl-methionyl-tRNA binding to ribosomes and the release ...
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Poulis, P.; Robecchi, G.; Kurochkina, A. O.; Felletti, M.; Rodnina, M. V. Recoding by N1-methylpseudouridine guides rational mRNA vaccine design. Nature Communications (2026).
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